Topic
Sarcopenia
Everything we've written on Sarcopenia — 6 articles covering the mechanism, the evidence, comparisons, and practical considerations.
6 articles
Metabolic healthBody recomposition after 35 — what changes and what worksYou're doing the things. The same things that worked before — the training schedule, the rough sense of eating well, the protein focus you picked up somewhere in your thirties. And yet the body composition is drifting in a direction you didn't authorize. The jeans fit differently. The waist measurement that held steady for years is up half an inch, then another. The scale might not have moved much, but the mirror tells a different story: less definition in the places you used to have it, more softness in the places you never did. You train harder for a month and the results are modest where they used to be unmistakable. You cut back on food and you're tired and irritable and the composition barely budges. The rules that governed your body for the first decade or two of serious training seem to have been quietly rewritten.9 min readAnti-aging and cellular healthHealthy aging in the 70s and 80s — what the peptide conversation looks like at this stageYou are seventy-five and you are, by most measures, doing well. You walk every morning. You see your grandchildren. Your last labs were good enough that your doctor barely discussed them. You're on a statin that you've been taking for twelve years and an antihypertensive that you adjusted to about three years ago, and maybe a low-dose aspirin that your cardiologist still recommends even though the guidelines have shifted. You've read something about peptides and longevity. Your son or daughter has mentioned them. And you want to understand whether any of this is relevant to you and your situation.9 min readAnti-aging and cellular healthPeptides in frailty — what the geriatric medicine evidence suggestsYou're watching your father lose weight he wasn't trying to lose. He gets tired walking to the mailbox, something that wasn't true eighteen months ago. He moves more carefully now, and the carefulness has a different quality than before — less deliberate, more uncertain. His grip strength is down. He's had one fall. His doctor says he's in the frailty range and talks about nutrition and maybe physical therapy. You've been reading about peptides and wondering if any of it applies to him.9 min readMetabolic healthThe body composition shift after 50 — what's really happening to muscle and fatIt's not exactly weight gain. That's what makes it hard to talk about, and hard to address. You step on the scale and the number is the same — within a few pounds of what it's been for years. But the mirror tells a different story. The upper arms are softer in a way that wasn't there before. The abdomen has shifted — not rounder, but different, a redistribution you can see even when you're not heavier. The legs feel different under the skin. The body at the same scale weight occupies space differently, and you're not sure when it started or what it means.8 min readMetabolic healthThe grip that's getting weaker — what disappearing hand strength is signalingThe jar is the first honest messenger. You twist, and it doesn't move, and you feel the effort travel up your forearm and find nothing to push against the way it used to. You run it under hot water, you use a towel for grip, you hand it to someone else. Then it's the kettlebell that sits differently in your palm, the handle harder to hold for the set than it was a year ago, your hand giving out before your legs or back do. Then it's the handshake — the firm, easy grip you delivered without thinking now requires a small deliberate squeeze to match what used to be automatic. Carrying the groceries, opening a bottle, holding a pull for more than a few seconds: somewhere in there, your hands got weaker, and you noticed.6 min readMetabolic healthThe strength that disappeared — what sarcopenia feels like before it showsThe jar thing happened first. Not dramatically — you noticed that your grip needed a second attempt, that you'd switched hands without thinking. Then the groceries: two trips instead of one, not because the bags were heavier but because something in the calculation had changed. The pushup count at the end of a workout is down from what it was, and not because you haven't been training. You've been training consistently. The numbers just don't move the way they did. Five years ago you'd put in four weeks of consistent resistance training and see results — actual changes in what you could lift, how your body looked, what felt hard. Now you're maintaining, barely, and the work that used to build feels like it's just holding the line against something. Your doctor says you're aging. Which is accurate. And also falls well short of explaining the mechanism or what you might do about it.8 min read